M. te Velde, Anthony Brummelkamp (1811-1888)

Tomás Hromádka , Anthony M . Zador and

Jorien Van Der Velde

BACKGROUND: Alexithymia (“no words for feelings”) is a psychological construct that can be divided in a cognitive and affective dimension. The cognitive dimension reflects the ability to identify, verbalize and analyze feelings, whereas the affective dimension reflects the degree to which individuals get aroused by emotional stimuli and their ability to fantasize. These two alexithymia dimensio...

Dmd057893 1811..1819

We have previously established an in silico classification method (“CPathPred”) to predict the major clearance pathways of drugs based on an empirical decision with only four physicochemical descriptors—charge, molecular weight, octanol-water distribution coefficient, and protein unbound fraction in plasma—using a rectangular method. In this study, we attempted to improve the prediction perform...

Op-brai130100 1868..1888

Functional magnetic resonance imaging has demonstrated reorganization of memory encoding networks within the temporal lobe in temporal lobe epilepsy, but little is known of the extra-temporal networks in these patients. We investigated the temporal and extra-temporal reorganization of memory encoding networks in refractory temporal lobe epilepsy and the neural correlates of successful subsequen...

MODERATOR : Anthony

Comment: There was angiocentric involvement, with atypical cells that were positive for the B cell marker CD20, with more benign appearing CD3 positive T cells also present. Reticulin stain showed reticulin proliferation about involved vessels. In situ hybridization of lesions showed strong positivity for EBV. Some members of the audience noted the presence of intranuclear inclusions in the les...